I actually have a tire with like a 1/2" x 1" hole, and I've been riding like this since last year.
What's my secret?
(1) Rim Strips
(2) Tire Strips (
like so)
(3) Thorn-Resistant Tubes
And not necessarily in that order.
Kevlar tires are also good, but they're likely the most expensive and the least likely to prevent flats. Not that they don't prevent flats, but thorns, glass, staples, nails, etc. are the things to look out for; hence, 2 & 3. And if you're a wheel bender... over time, spokes are just as likely to become a staple or nail of sorts.
Links to Amazon may include affiliate code. If you click on an Amazon link and make a purchase, this forum may earn a small commission.