There are quite a few bicyclist blogs on the Internet. Some have made trips without even a 49cc engine from the Pacific to the Atlantic. Some travel with only 2 paniers, while some pull small trailers. The difference between a bicycle and a motor bicycle is what you or someone else attached to it.
You need to a be decent mechanic, able to diagnose and fix your engine problems. If you breakdown, you will need a supply source, someone that can overnight ship you what you need, up to and including a new engine kit. A good basic tool kit, along with a few extra "parts" like an extra tire, inner tube, a flat kit with lots of patches, etc.. If you break down in the middle of nowhere and need a part or supply, call your supply base and have it sent general delivery to the next town's post office. It may take 2 days, but you will be on your way. A cell phone with an extra battery will be a lifesaver.