for a person willing to take time and work carefully, most anything can be done - I've done some heavy stuff like that in the past, but can't really afford the time to do all the custom work these days
from the pic, it looks like getting the motor in there will be too tight for standard mounts and maybe a lay shaft (or two) will be needed to clear that tire and get back in to the the hub again - jack shafting to the pedal side should work, but seems a shame to waste that on a one speed
OTOH, I really love to see nicely turned out projects like that