I've used them on my regular/non-motorized bicycle. Personally, I don't like them. They don't absorb shock as well and the version that is an entire tire, squirms on the rim and simply doesn't feel right. The other version that goes inside the tire seems better, but still doesn't abosorb shock nearly as well, (no even close), so I've written them off.
However, there are others in this forum that like them, so I'll leave it to them for more positive information.
In my opinion, I don't think there's much worry about a blow out. I ride my standard bicycle 30mph, and I haven't had a problem. I do know of someone it happened to, but he managed to maintain control after hitting a BIG pothole, so he wasn't hurt. His roadbike is far better than my beater, so he was going around 42mph. It could have been much worse.
--John