The most secure mount is always a V-frame bicycle like the instructions call for. Barring that, most cruisers come with a curved downtube and the muffler clamp adapters, although somwhat less secure, is going to work OK.
I could see that someone could just add a couple 1 & 1/2" hose clamps on either side of the U-bolt shank if you're concerned that the front clamp will slide, It shouldn't in most cases, as the seat tube takes most of the driving forces from the engine.
V-frame bikes though are the ideal set up.