2-stroke FTW!
I've got a 4-stroke, but I don't wanna put it on 'til the 2-stroke stops running. 4-strokes have their advantages, but not having to mix gas is the only benefit that I wish I could do... but then again, I don't think changing oil would be too much fun either. Then 4-strokes also need valve adjustments every once in awhile... also no fun.
Speed, keeping my folding bike light and "tilt proof" so that oil doesn't leak outta the crankcase, and mostly maintenance free are my main concerns. Also, it's nice to ride WOT all the time and not worry about the engine blowing up. Supposedly, attempting to go on a cross-country road trip with these small 4-strokes & no transmission wouldn't get you very far.
IMHO... 2-stroke, rack-mount, & chain or friction drive are the ways to go.
And, uh, Heath... what 4-stroke do you have that's getting 15k rpm??