Some immediate drawbacks:
* $1,550!
http://www.rotarybike.com/rotarybike_products.asp?type=Petrol
* 2 stroke = dirty
* 18 lbs!!
* You need to use their wheel rather than your own. Durability? Weight? Gearing? Brakes?
This design was originally made by Sachs, but I apparently they sold off this particular division several years ago and the current iteration is made in Taiwan to the same or similar specs. This would suggest that the design is relatively proven, and probably reliable.
One nice feature is electric start. Which would make it (conceivably) easy to use the assist only on uphill sections instead of having to leave it idling for most of a ride.