the first thing to do is determine what size jet is in the carb now. the majority of the jets in the stock n.t. carbs are not marked with a size number, but i think someone estimated them at being a .70 jet. if you have the cns carb, i have no idea what jet is in it or what jets will fit it.
the thing about drilling out a jet is that it's real easy to go too big with the hole size.
it's all trial and error and if you do go too big, you can always solder the hole closed and re-drill it smaller. but a smaller hole will make it leaner and you don't want that. a slight change in the hole size can make a huge difference, especially when you are heading toward the lean side.
I bought delorto jets from sick bike parts instead of drilling out my stock jet. HOWEVER, the jets do not screw into the stock n.t. carbs easy. the pitch of the threads is slightly different and the jets screw in tight. They fit, but they are tight and you take a chance of messing up the threads in the carb where the jet screws in.
for example, on one of my engines, my stock main jet was (i'm guessing) a .70 and it was running too lean with my modified exhaust. so to determine that i had around a .70 jet in it, i threw in a .68 jet to give me a baseline.
well, the .68 made it leaner,(popping, bogging at w.o.t. and my plug was a silvery color) so i knew that the stock jet was around a .70.
from there i went up in jet sizes starting with a .72, which made a slight difference.
then i went to a .74 which made a huge difference and it ran great.
then, i went up to a .76 just to see if i could fine tune it a little more, and the .76 was too rich (it started 4 stroking at w.o.t., and my plug was black). i dropped back down to the .74 and that's where i left it. my plug is always tan, no 4 stroking and no popping. i think i have my jet needle clip set right around in the middle, but it's been awhile and i kind of forgot where it's set.
I also have a high flow air filter on it which helps the engine breath a lot better than the stock filter.
now, this jet change didn't make me gain 10 mph or anything crazy like that, but it did make a difference in how the engine starts, runs and accelerates.
i may have gained 5 mph from the jet change, modified exhaust and high flow filter, but it may not even be 5 mph...i'm not really sure.